Seronegative Rheumatoid Arthritis: What Is It And Its Treatment Options

Seronegative Rheumatoid Arthritis: What Is It And Its Treatment Options

There are people who have symptoms of rheumatoid arthritis, but unfortunately, the test results come back as normal, i.e., the reports do not show RA factor in the blood. In that case, they might be having seronegative arthritis.

According to the World Health Organisation (WHO), about 18% of people live with rheumatoid arthritis, out of which 70% are women. So, what is the disease all about? Let’s understand that first.

Rheumatoid arthritis (RA) is a chronic inflammatory and autoimmune condition that mainly happens when the immune system of an individual fails to work properly and starts attacking the lining of the joints. The condition is usually present with pain in the joints, though sometimes, it might affect other parts of the body such as the eyes, lungs, skin and heart, says Dr. Amitabha Saha, a top rheumatoid arthritis doctor in Kolkata.

The common diagnostic procedure to detect rheumatoid arthritis is through a blood test that checks for RA factors and anti-CCP antibodies present in individuals with this condition. The test results that usually come out are of two types: seropositive and seronegative.

When You Are Diagnosed With Seronegative Arthritis

If you are seronegative for rheumatoid arthritis, it makes it difficult for health providers to diagnose your condition. Being seronegative means that your body either does not have RA factor or anti-CPPs at all, or it might be present in negligible amounts, which is not enough to confirm the condition. In that case, a rheumatoid arthritis doctor in Kolkata recommends additional tests to look for inflammation or joint damage.

Recent research even suggests that people who are prone to gaining weight or who smoke regularly are more likely to have seronegative rheumatoid arthritis.

What Are The Symptoms Of Seronegative Arthritis?

No matter whether you have seropositive or seronegative arthritis, the symptoms of both types are quite similar.

  • Joint stiffness, especially that of the hands, knees, ankles and hips, especially during the morning.
  • Tenderness and swelling in the joints
  • Persistent inflammation in the body
  • Muscle fatigue

What Are The Symptoms Of Seronegative Arthritis? | rheumatoid arthritis doctor in Kolkata

In some cases, patients with seronegative rheumatoid arthritis have milder symptoms than those with seropositive rheumatoid arthritis. However, that’s not the case for all individuals. It is to be noted that these symptoms vary over time and affect individuals differently.

What Are The Treatment Options For Seronegative Rheumatoid Arthritis?

The treatment option for seronegative rheumatoid arthritis is similar to seropositive. The techniques mainly focus on reducing the severity of the symptoms and preventing further progress of the condition to reduce complications. Some common treatment approaches include the following:

  • Medicines: Your doctor will prescribe Nonsteroidal anti-inflammatory drugs (NSAIDs) to reduce the swelling and pain associated with joint inflammation. They also alleviate joint stiffness, thereby improving mobility issues.
  • Regular Exercise: Low-impact exercises like swimming, stretching, walking and cycling build muscle strength and keep the joints in motion.
  • Therapy: Physical therapy includes learning new methods to move your body in certain ways that help with pain relief and improve flexibility.
  • Surgery: This is probably the last resort for patients with an increased risk of cartilage and joint damage. They may need to undergo joint replacement or joint fusions to reduce pain and restore physical function.

Final Words

Arthritis is hard to diagnose for patients whose test reports come out as seronegative. Hence, as soon as you start experiencing joint pain, make sure to consult a rheumatoid arthritis doctor in Kolkata. The earlier you begin with the treatment plan, the more likely you will go into remission than those who are delayed.